A 12-year-old boy with a peanut allergy is brought to the emergency room after accidental consumption of peanuts. He is in anaphylactic shock. Which of the following drugs is most appropriate to treat this patient?
A. Norepinephrine
B. Phenylephrine
C. Dobutamine
D. Epinephrine
D
D . Epinephrine because in anaphylactic shock there is rapid drop of pulse due to release of flood chemicals by our immune system .
D
Adrenaline
THE CORRECT ANSWER – D : EPINEPHRINE
EXPLANATION : Norepinephrine has more α agonistic effects and activates mainly α1, α2, and β1 receptors.
Epinephrine has more β agonistic effects and activates mainly α1, α2, β1, and β2 receptors.
Phenylephrine has predominantly α effects and activates mainly α1 receptors.
Dobutamine mainly activates β1 receptors and has no significant
effects on β2 receptors.
Thus, epinephrine is the drug of choice in anaphylactic shock that can both stimulate the heart (β1 activation) and dilate bronchioles (β2 activation).